Victor Zepeda

Victor Jimenez-Zepeda, MD

Positions

Assistant Professor

Cumming School of Medicine, Department of Medicine

Member

Arnie Charbonneau Cancer Institute

Contact information

Web presence

Phone number

Office: 403.944.5247

Admin Assistant

Ivana Ellsworth

Email: ivana.ellsworth@ahs.ca

Office: 403.944.1564

Background

Biography

Dr. Jimenez-Zepeda currently holds an academic position as Assistant Professor of Medicine at the University of Calgary and Clinician Scientist for the Tom Baker Cancer Center in Calgary, AB, Canada. He completed medical school at the University of Guadalajara in Mexico, and took Internal Medicine and Hematology training at the National Institute of Medical Sciences and Nutrition in Mexico City. He obtained specialized training in lymphoma and myeloma and had the opportunity to undergo an elective training in hematology at the Cleveland Clinic Foundation from March to May, 2004 under the mentorship of Dr. Gordan Srkalovic, where he learned about the fascinating biological aspects of a rare disease for hispanic population called Multiple Myeloma. He also went onto receive further training in hematology under the mentorships of Drs. Joan Blade and Armando Lopez-Guillermo in Barcelona, Spain in 2006. From 2007-2009, obtained bench training in genetics and myeloma under the supervision of Drs. Rafael Fonseca, Keith Stewart and Leif Bergsagel at the Mayo Clinic in Scottsdale, Arizona, where he received a grant award with a project of IL-6 and hepcidin in Waldenstrom Macroglobulinemia funded by the International Waldenstrom’s Macroglobulinemia Foundation.

Dr. Zepeda joined the myeloma research group at the Princess Margaret Hospital in July of 2009 as a clinical research fellow and quickly expressed interest in research projects in both the clinical and basic field. He was awarded with the MMRF Research fellow award with a project on STAT3 inhibition in Multiple Myeloma that was presented at the ASH meeting in 2012 and had published ~20 clinical and basic science related manuscripts back from his stay at the Princess Margaret Hospital. He was also awarded the ASH Abstract achievement award in 2012. As part of his clinical fellowship at Princess Margaret Hospital in Toronto, he participated in the building process of a comprehensive database for plasma cell dyscrasias and received recognition in the form of abstract presentations in many scientific meetings. He received the Young Investigator Research Award in the year of 2010 as part of the Canadian Conference of Lymphoproliferative disorders. Dr. Zepeda has more than 100 journal publications and abstracts to his credit. He has served as a reviewer for Journal of Clinical Oncology, American Journal of Clinical Oncology, British Journal of Hematology, Annals of Hematology, International Journal of Laboratory and Clinical Hematology, Leukemia Lymphoma Journal, Journal of Pathology and the World Journal of Surgical Procedures among others.

Currently, Dr. Zepeda is the clinician leader for the Amyloid program in Calgary, AB and has received funding from the Alberta Health Services Foundation to build up a provincial database in collaboration with Dr. Chris Venner in Edmonton, AB. He functions as a Principal Investigator and Sub-PI for many clinical trials on Myeloma and Amyloidosis at the Tom Baker Cancer Center. Along with other myeloma investigators from Calgary, he is interested in elucidating the mechanisms of resistance associated to ImIDs and is co-investigator in a project of rheovirus as an immune therapy alternative for patients with Multiple Myeloma and was recently awarded with a grant funded by the Cancer Research Society and Myeloma Canada. In addition, he is the clinician lead for AL Amyloidosis in Calgary and currently is on a sabbatical leave in Pavia, Italy working in a few amyloid research projects that hopefully will help build a more robust amyloid program upon his return to Calgary. He serves as member of the steering committee for the Myeloma Canada Research Network Database and is member of other prestigious international societies such as the International Myeloma Society, European Hematology Association, American Society of Hematology among others.

Research

Areas of Research

Area of Focus
  • Amyloidosis and Multiple Myeloma
Activities

Currently Dr. Zepeda along with other hematologists has built one of the biggest MGUS clinics in Canada aiming to assess monoglonal gammopathies of clinical significance in a more expedite fashion and is one of the few centers with an amyloid screening program.

Number of publications: PUBMED 52 Original articles, 3 Review Articles, 4 Book Chapters

Abstracts presented in major meetings: ~100 (ASH, EHA, Amyloid symposiums, etc.).

Funded Research:

  • Next generation immune treatment strategies for multiple myeloma: immune modulators in conjunction with oncolytic viral therapy, awarded by the Cancer Research Society and the Myeloma Canada Foundation, 120,000 CAD over a 2-year period (2016-2017) (Co-PI Dr Don Morris and Dr Stewart)
  • Building a comprehensive database on plasma cell disorders, co-investigator, 220,000 CAD, Co-Investigator, clinical lead, Calgary
  • Utilization of Freelite and Hevylite in the risk stratification and monitoring of patients with newly diagnosed intact immunoglobulin multiple myeloma, 24,720 CAD, Co-Investigator
  • Multiple Myeloma Research Foundation (MMRF) Research Fellow Grant Award (75,000 USD) with the project entitled STAT3 inhibition and multiple myeloma, Principal Investigator, 2011
  • Grants for nursing education in plasma cell disorders, 10,000 CAD
  • Educational grants in 2015 to attend preceptorships in Barcelona and Salamanca, Spain, 20,000 CAD

Awards

  • award, 2015
  • award, 2014
  • award, 2013
  • award, 2012
  • award, 2011
  • award, 2010
  • scholarship, 2008

Publications