Tak Ho Chu
PhD
Positions
Adjunct Research Assistant Professor
Cumming School of Medicine, Department of Clinical Neurosciences
Research Associate
Cumming School of Medicine, Department of Clinical Neurosciences
Associate Member
Hotchkiss Brain Institute
Contact information
Background
Educational Background
PhD Neuroscience, University of Hong Kong,
BSc Biology, Hong Kong University of Science and Technology,
Projects
Research Activities
My research interests are in peripheral nerve injuries and repair. My major focus is on how Schwann cells, glial cells in the peripheral nervous system, support neuron survival and axon regeneration after injury as well as how they contribute to the progression of diseases. Currently, I am using cell culture and animal models to study how Schwann cells derived from human tissues can help with the repair process.
Publications
- Novel AAV variants with improved tropism for human Schwann cells. Matthieu Drouyer, Tak-Ho Chu, Elodie Labit, Renina Gale Navarro, Deborah Nazareth, Nicole Rosin, Jessica Merjane, Suzanne Scott, Marti Cabanes-Creus, Adrian Westhaus, Erhua Zhu, Rajiv Midha, Ian E. Alexander, Jeff Biernaskie, Samantha L Ginn, Leszek Lisowski. Molecular Therapy Methods & Clinical Development. (2024)
- Perineurial windows is critical for experimental reverse end-to-side nerve transfer. Tak-Ho Chu, Saud Alzahrani, Amanda McConachie, Nicolas Lasaleta, Amira Kalifa, Rajesh Pathiyil, and Rajiv Midha. Neurosurgery. (2023)
- Comparison of human skin- and nerve-derived Schwann cells reveals many similarities and subtle genomic and functional differences. Tak-Ho Chu, Kabita Baral, Elodie Labit, Nicole Rosin, Sarthak Sinha, Daniel Umansky, Saud Alzahrani, Rohit Arora, Leslie Cao, Derrick Rancourt, Jeff Biernaskie and Rajiv Midha. Glia. (2022)
- Successful retrograde regeneration using a sensory branch for motor nerve transfer. 27. Saud Alzahrani, Harley Brito da Silva, Tak-Ho Chu, Zain Tariq, Daniel Umansky, David Elliot and Rajiv Midha. Journal of Neurosurgery. (2022)
More Information
Are you the profile owner?
Login to edit.