Dr. Shamir Chandarana

Shamir Chandarana



Clinical Associate Professor

Cumming School of Medicine, Department of Surgery


Cumming School of Medicine, Head and Neck Program


Arnie Charbonneau Cancer Institute

Contact information

Phone number

Office: 403.944.3954


Office: ENT Clinic, 1820 Richmond Road SW, Calgary, AB T2T 5C7

Preferred method of communication

Admin Assistant

Kim Osborne

Email: kim.osborne@ahs.ca

Office: 403.944.3954



Dr. Chandarana completed Medical School and Otolaryngology-Head and Neck Surgery residency training at Western University in London, Ontario. He then pursued a 2-year fellowship in Head and Neck Cancer Surgery and Microvascular Reconstruction at the University of Michigan. Concurrently he also completed a Masters in Public Health. In 2010, Shamir joined the section of Otolaryngology-Head and Neck surgery at the University of Calgary and is a core member of the Head and Neck Surgery Program. He enjoys a busy practice focused on head and neck cancer surgery, thyroid/parathyroid surgery and reconstructive surgery. His research interests include clinical outcomes in head and neck surgery, biomarker research and epidemiology of thyroid cancer surgery.


Areas of Research

Area of Focus
  • Thyroid Cancer
Summary of Research

Dr. Chandarana's current research interests include biomarker expression in lymph node metastasis from head and neck squamous cell carcinoma (markers of more aggressive tumors), functional outcomes after major head and neck surgery, clinical care pathway to streamline complex treatment algorithms, and epidemiologic practice patterns in management of thyroid cancer. 


More Information

Dautremont JF, Rudmik LR, Chandarana SP, Dort JC et al. Understanding the impact of a clinical care pathway for major head and neck cancer resection on postdischarge healthcare utilization. Head and Neck (epub ahead of print) 2015 Sept: doi: 10.1002/hed.24196.

Deutschmann MW, Chin-Lenn L, Au J, Brilz A, Nakoneshny S, Dort JC, Pasieka JL, Chandarana SP. Extent of Central Neck Dissection among Thyroid Cancer Surgeons: A Cross-sectional Analysis. Head and Neck (epub ahead of print) 2014 Dec; doi: 10.1002/hed.23996.

Dang M, Chandarana SP, Dort JC et al. MRI Texture Analysis Predicts p53 Status in Head and Neck Squamous Cell Carcinoma. Am J Neurorad 2015 Jan; 166-70.

Randall DR, LysackJT, Hudon ME, Guggisberg K, NakoneshnySC, MatthewsTW, Dort JC, ChandaranaSP. Diagnostic utility of central node necrosis in predicting extracapsular spread among oral cavity squamous cell carcinoma Head and Neck 2015; 31(1):92-6, PubMed ID 24327459.

Randall DR, Park PS, Chandarana SP, Chau J. Proteomic Analysis of Human Stapes in Otosclerosis. Otolaryngol Head Neck Surg 2014 Sep; 151(1):94-95.

Lui JT, Khalil MN, Chandarana SP. Primary Squamous Cell of the Thyroid – An Abbreviated Presentaiton. J Otolaryngol Head and Neck Surg 2014 Jun; 43:17.

Yeung J, Dautremont J, Harrop R, Asante T, Hirani N, Nakoneshny S, De Haas V, McKenzie D, Matthews TW, Chandarana SP, Schrag CH, Dort JC. Reduction of Pulmonary Complications and Hospital Length of Stay with a Clinical Care Pathway after Head and Neck Reconstruction: A Prospective Comparative Observational Study. Plast Reconstr Surg 2014 Jun; 133(6):1477-84.

Liu CC, Hoy M, Matthews TW, Guggisberg K, Chandarana SP. Pilomatrix Carcinoma of the Head and Neck: Case Report and Literature Review. Head and Neck Oncol 2014 May 03; 6(2):12.

Dautremont JF, Yeung J, AsanteT, NakoneshnySC, Hoy M, LuiA, Chandarana SP, Matthews TW, Schrag CH, Rudmik LR, Dort JC. Cost-effectiveness analysis of a post-operative clinical care pathway in head and neck surgery with microvascular reconstruction. J Otolaryngol Head and Neck Surg. 2013 Dec: 42:59 doi:10.1186/1916-0216-42-59.

Lysack, JT, Hoy MH, Hudon ME, Nakoneshny SC, Chandarana SP, Matthews TW, Dort JC. Impact of Neuroradiologist Second Opinion on Staging and Management of Head and Neck Cancer. J Otolaryngol Head and Neck Surg. 2013 Jun; 42(1): 39.

Cho J, Taylor RC, Deutschmann M, Chandarana S, Marck PA. Polyethylene Implants in Nasal Septal Restoration. JAMA Facial Plast Surg. 2013 Jul; 15(4): 275-9.

Deutschmann M, Khalil M, Bhayana S, Chandarana S. Occult multifocal papillary thyroid microcarcinoma presenting as a supraclavicular mass containing anaplastic thyroid carcinoma. JAMA Otolaryngology Head Neck Surg. 2013 Apr; 139(4):415-8.

Chin CJ, Franklin JH, Turner B, Moukarbel RV, Chandarana S, Fung K, Yoo J, and Doyle PC. A Novel Tool for the Objective Measurement of Neck Fibrosis: Validation in Clinical Practice. J Otolaryngol Head Neck Surg. 2012 Oct; 41(5):320-6.

Chandarana S, Chanowski EJP, Casper KA, Wolf GT, Bradford CB, Worden FP, Eisbruch A, Chepeha DB. Osteocutaneous Free Tissue Transplantation for Mandibular Osteoradionecrosis.  Journal of Reconstructive Surgery 2012 Oct; Epub ahead of print DOI: 10.1055/s-0032-1326731

Klimowicz AC, Bose P, Nakoneshny SC, Dean M, Huang L, Chandarana S, Magliocco AM, Matthews TW, Brockton NT, Dort JC. Basal Ki67 expression measured by digital image analysis is optimal for prognostication in oral squamous cell carcinoma. European Journal of Cancer 2012 Sep; 48(14):2166-74.

Chandarana S, Lee JS, Chanowski EJP, Sacco AG, Bradford CR, Wolf GT, Prince ME, Moyer JS, Eisbruch A, Worden FP, Giordano T, Kumar B, Cordell KG, Carey TE, Chepeha DB. Prevalence and Predictive Role of p16 and EGFR in Surgically Treated Oropharyngeal and Oral Cavity Cancer Head and Neck 2012 Aug; Epub ahead of print DOI: 10.1002/hed.23087.

Bose P, Klimowicz AC, Kornaga E, Petrillo SK, Matthews TW, Chandarana S, Magliocco AM, Brockton NT, Dort JC. Bax expression measured by AQUA analysis is an independent prognostic marker in oral squamous cell carcinoma. BMC Cancer 2012 Aug; 12(1):332.

Chandarana S. Practical Approach: Head and Neck Cancer: Red Flags in the Family Practice Setting. Canadian Journal of Diagnosis. 2012 Aug;29(7):53-55.

Brockton NT, Klimowicz AC, Bose P, Petrillo SK, Konno M, Rudmik L, Dean M, Nakoneshny SC, Matthews TW, Chandarana S, Lau HY, Magliocco AM, Dort JC: High stromal carbonic anhydrase IX expression is associated with nodal metastasis and decreased survival in patients with surgically-treated oral cavity squamous cell carcinoma. Oral Oncology 2012 Jul; 48(7):615-22.

Chandarana S, Yoo J, Fung K, Franklin J, Nichols A, Doyle PC. The use of autologous platelet and plasma products in salvage neck dissections: a prospective clinical study evaluating early and late wound healing. Journal of Biological Regulators and Homeostatic Agents 2012 Apr;26(2):63-70

Wheeler B, Doyle PC, Chandarana S, Agrawal S, Husein M, Ladak H. Interactive computer-based simulator for training in blade navigation and targeting in myringotomy. Computer Methods and Programs in Biomedicine. 2010 May;98(2):130-9.

Zhao X, Chandarana S, Husein M, Rogers J, MacRae D. Surgical distance to the sphenoid sinus: a comparison of healthy patients and patients with cystic fibrosis. Archives of Otolaryngology, Head and Neck Surgery. 2010 May;136(5) 475-9.

Patel S, Chandarana S, Husein M, Chan, N. Diagnosis and management of a neonatal intralingual cyst of foregut origin. International Journal of Pediatric Otorhinolaryngology. 2010 Jan;5(1) 1-4.

Chandarana S, Chanowski EJP, Casper KA, Moyer JS, Lee J, Chepeha DB. Osseocutaneous transplantation for mandibular osteoradionecrosis (abstract). Oral Oncology Supplement. 2009 July;3(1) 87.

Zhao X, Chandarana S, Husein M, Kwan K. Congenital Epulis – An atypical presentation: case report and review of literature.  Journal of Otolaryngology – Head and Neck Surgery. 2009 Apr;38(2)E65-8.

Chandarana S, Fung K, Franklin J, Kotylak T, Matic D, Yoo J. Effect of autologous platelet adhesives on dermal fat graft resorption following reconstruction of a superficial parotidectomy defect: a double-blinded prospective trial. Head and Neck. 2009 Apr;31(4)521-30.

Yoo J, Chandarana S, Crosby R. Clinical application of tissue adhesives in soft-tissue surgery of the head and neck. Current Opinion in Otolaryngology & Head & Neck Surgery. 2008 Aug;16(4)312-7.

Chandarana S,  Parnes L, Agrawal S, Fung K. Quality of life following small fenestra stapedotomy. Annals of Otology, Rhinology & Laryngology. 2005 June;114(6)472-7.

Sindwani R, Wright ED, Janzen V, Chandarana SPerioperative management of the sinus patient:  a Canadian perspective. Journal of Otolaryngology. 2003 June;32(3)155-59.

Han VKM, Carter AM, Chandarana S, Tanswell B, Thompson K. Ontogeny of expression of insulin-like growth factor (IGF) and IGF binding protein mRNAs in the guinea-pig placenta and uterus. Placenta. 1999 May;20(4)361-77.