Dr. Raymond William Turner
Positions
Professor (Research)
Cumming School of Medicine, Department of Clinical Neurosciences | Translational Neuroscience
Full Member
Hotchkiss Brain Institute
Child Health & Wellness Researcher
Alberta Children's Hospital Research Institute, Owerko Centre
Contact information
Phone number
Office: 403-220-8452: Lab: 403-220-8451
Location
Preferred method of communication
All topics: Email.
Background
Educational Background
PhD Neurophysiology, University of British Columbia, 1985
Postdoctoral Research, National Institutes of Health, Bethesda, MD, 1989
Postdoctoral Research, University of Ottawa, Ontario, 1991
More Information
Dr. Ray Turner’s work focuses on neuronal membrane excitability through studies at the molecular to physiological levels in animal models, and on a new potential therapeutic treatment for the genetic disorder Fragile X Syndrome (FXS). They discovered that a fragment of the missing protein, FMRP, can be reintroduced to the brain by attaching a cell permeable peptide (tat) to cross the blood brain barrier and enter neurons across the brain axis. Remarkably, FMRP N-tat restores ion channel function in the cortex and cerebellum and circuit level output (EEG) in the neocortex of a FXS mouse model for days after a single injection. The success of this work has attracted a donor who has formed a company (BowensFX) to rapidly push these fragments towards initial clinical trials to achieve a translational outcome. Dr. Turner’s research is currently funded by CIHR, NSERC, DCNS/HBI, and FRAXA.
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