Dr. Ning Cheng

Autism is one of the most prevalent neurodevelopmental disorders both in Canada and worldwide. It causes significant social, communication and behavioral challenges. Currently, no cure exists for autism. The overarching goal of my research program is to elucidate the mechanisms underlying the core symptoms and to identify potential therapeutics for autism. To achieve this goal, we will utilize animal models of autism and related disorders such as fragile X syndrome. We will perform in vivo recording and modulation of brain activities, combined with simultaneous behavioral assessment. In addition, we will collect tissue for biochemical, electrophysiological, molecular, and anatomical analysis. These translational studies will contribute to our understanding of the pathophysiology of autism and related disorders in a manner that cannot be accomplished in human populations. Ultimately, this new understanding will lead to development and testing of novel treatments for these disorders, which is desperately needed to reduce the burden of affected individuals, their families, and our society.