BSC, MSC DVM, Ph.D Motamed Ali
Affiliations
Research Assistant
University of Calgary
Contact information
Web presence
Phone number
celluar : 5875798206
Preferred method of communication
email: motamed.ali@ucalgary.ca, email: motamed71111@gmail.com
Whatsapp: +1 587-579-8206
Background
Credentials
Ph.D. in Veterinary Medicine, Assiut University, Egypt- Gifu University, Japan (Joint supervision), 2006
Pending Licensure – Alberta Veterinary Medical Association (ABVMA), ABVMA,
Educational Background
Ph.D. in Veterinary Medical Sciences Assiut University (Egypt)- Gifu University- Japan (Joint supervision), 2006
Master of Veterinary Medical Sciences Assiut University, 1999
Bachelor of Veterinary Medical Sciences Assiut University, 1995
Biography
I am an expert in immunovirology with expertise in host–pathogen interactions and innate immune modulation by intracellular pathogens, with over 20 years of research and teaching experience in infection biology, immunopharmacology, and host–pathogen interactions. My interdisciplinary research integrates molecular immunology, virology, neuroinflammation, and natural product pharmacology to investigate immune modulation and therapeutic discovery. My research journey spans animal modeling, molecular laboratory techniques, cell culture, imaging tools, and behavioral profiling to identify compounds and mechanisms that enhance immune function. I have also held various leadership and administrative roles, including serving as Dean of a Veterinary College, Vice Dean, and Head of Department for about seven years in total.
- At the University of Calgary, I have demonstrated how avian coronaviruses exploit the COX-2/PGE2 inflammatory pathway to impair host defense. Using tracheal organ cultures and targeted immune assays, I identified novel therapeutic targets, including prostaglandin receptors and JAK-STAT modulators, that hold promise for host-directed antiviral interventions.
- At the National Research Center for Protozoan Diseases in Japan, I have led preclinical studies illustrating how chronic Toxoplasma gondii infection contributes to depression-like behaviors and cognitive dysfunction. I revealed that IFN-γ–driven IDO activation disrupts serotonin metabolism and alters brain circuitry, uncovering a novel link between neuroinflammation and infection-induced psychiatric outcomes.
- At Gifu University, I explored how natural bioactive compounds—including capsaicin, Calotropis procera, and Agaricus blazei—regulate immune responses. My studies uncovered TRPV1-independent pathways through which these agents suppress fever and inhibit IFN-γ–induced antigen presentation, highlighting their therapeutic potential as anti-inflammatory and immunomodulatory agents.
Projects
Joint Supervision Scholarship, Japan, Executive Fellow, funded by the Egyptian Government, Aug 2004 – Dec 2006 | Total: $36,000 CAD, Awarded for collaborative doctoral research in Japan under international academic partnership.
Postdoctoral Fellowship, Japan, Fellow, funded by the Japanese Government, Mar 2007 – Mar 2008 | Total: $18,000 CAD, Conducted advanced research in molecular pharmacology and host-pathogen interactions.
Personal Research Grant, USA, Co-Principal Investigator, Joint Research Grant with University of Illinois, 2009 | Total: $9,000 USD, Supported collaborative research in comparative immunopharmacology.
Educational Development Project, Egypt, Executive Manager, Funded by the Ministry of Higher Education, 2010 – 2012, Development of Student Assessment System, Sohag University, Faculty of Veterinary Medicine.
Postdoctoral Fellowship, Japan, Fellow, funded by the Japanese Government, Sept 2012 – Jan 2015 | Total: $54,000 CAD, Focused on pharmacogenomic responses in veterinary species.
Expert Appointment, China, Foreign Expert, Three-Thousand Talent Program (SOFEA)
Aug 2015 – Jan 2016 | Total: $30,000 CAD, Invited as an international expert for veterinary education and research development.
Educational Enhancement Project, Egypt, Executive Manager, Funded by the Ministry of Higher Education, 2018 – 2020, Development and Enhancement of Educational System, Sohag University, Faculty of Veterinary Medicine.
Postdoctoral Fellowship, Egypt, Fellow, funded by the Egyptian Government
Jul 2022 – Jan 2023 | Total: $15,000 CAD, Research in host immune responses to viral pathogens.
Postdoctoral Fellowship, Canada, Fellow, funded by the Canadian Government
Feb 2023 – Jun 2024 | Total: $45,000 CAD, Conducted research in veterinary virology and pharmacological immune modulation, University of Calgary.
July 2024 – July 2025 | Total: $45,000 CAD, Research Assistant, Conducted research in veterinary virology and pharmacological immune modulation, University of Calgary
Awards
- Awarded 2020 Scientific Excellence, , Sohag University, Egypt . 2020
- 2nd leading role in Environmental Services, , Sohag University, Egypt . 2018
- Highest Citation in the Faculty of Vet. Medicine, Sohag University, Egypt , Sohag University, Egypt . 2018
- Sohag University Prize for Promotion of Sciences, in Veterinary and Agricultural Sector, , Sohag University, Egypt . 2012
- Best Oral Presentation, Egyptian Society of Cattle Disease Conference, , Assiut University, Egypt.. 2008
- Best Master thesis, 6th October University, Cairo, Egypt., 6th October University, Cairo, Egypt.. 2002
- Best student Review article, Egyptian Society of Cattle Diseases Society, Assiut University, Egypt. , Egyptian Society of Cattle Diseases Society. 1997
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