Minh Dang Nguyen

Dr. Minh Dang Nguyen




Cumming School of Medicine, Department of Clinical Neurosciences | Translational Neuroscience

Co-Director Graduate Program of Neuroscience

Cumming School of Medicine, Department of Clinical Neurosciences

Full Member

Hotchkiss Brain Institute

Child Health & Wellness Researcher

Alberta Children's Hospital Research Institute

Contact information

Web presence

Phone number

Office: +1 (403) 210-5494

Preferred method of communication



Educational Background

B.S. Biochemistry, University of Montreal, 1997

Doctor of Philosophy Neurosciences, McGill University, 2002

Post-doc Cell Biology, Harvard University, 2005


Areas of Research

Molecular Mechanisms

What happens in our brains as we age? This is a critical question that drives the research of my laboratory at the University of Calgary since September 2005. The main goal of my research program is to understand the basic mechanisms governing brain aging and neurodegenerative disorders; the increased age being the main risk factor for neurodegeneration. To tackle these two problems, we use a very basic molecular cell biology approach to study the neuronal cytoskeleton (the internal scaffolding that provides structure for the cell, as well as transports materials and sends signals to other parts of the cell) and its associated signaling proteins. Mutations or alterations in the neuronal cytoskeleton can lead to premature aging and neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis. This work sometimes leads us to revisit the physiological functions of these molecules such as during neuronal development, maturation, plasticity and investigate their potential to promote repair.

Participation in university strategic initiatives


Gut-Brain Axis in Neurodegeneration

Cerebrovascular Dysfunction in Alzheimer's Disease