Joe Kendal

Joseph Kendal



Clinical Assisant Professor

Cumming School of Medicine, Department of Surgery | Orthopedic Surgery

Full Member

McCaig Institute for Bone and Joint Health

Full Member

Arnie Charbonneau Cancer Institute

Contact information

Web presence

Phone number

Office: 403.944.4793


Office: HRIC3A25

Preferred method of communication

Administrative Assistant

Nandini Bhowmick

Office: 403.944.4793



Dr. Joseph Kendal is an Orthopaedic Surgeon specializing in the management of adult and pediatric musculoskeletal oncology patients. This includes a wide spectrum of bone and soft tissue tumours, including sarcoma and metastatic bone disease. Dr. Kendal was born in Calgary and completed his medical school, graduate school, and orthopaedic surgery residency training at the University of Calgary, followed by a two-year combined research and clinical fellowship in orthopaedic oncology at the University of California, Los Angeles (UCLA). His academic interests lie in improving outcomes in patients with metastatic bone disease and sarcoma through clinical and translational research initiatives. 


Areas of Research

Area of Focus
  • Musculoskeletal Oncology
  • Surgical management of metastatic bone disease
  • Tumour immunology and intralesional drug delivery
  • B-cells and tertiary lymphoid structures
Summary of Research

The vision of our research program is to improve clinical outcomes for patients with MBD through evidence-based clinical pathways and novel clinical and translational research initiatives. Our translational program will be focused on pre-clinical modelling of metastatic bone disease using benchtop and in vivo models to further our understanding of disease mechanisms and effectiveness of novel therapies such as immunotherapy. Metastatic bone lesions have a discordant response to novel targeted therapies and immunotherapy compared to visceral or primary lesions, and we aim to elucidate mechanisms for this discrepancy and to evaluate strategies to modulate the local tumour immune microenvironment (TIME) to increase MBD lesion sensitivity to treatment. We aim to incorporate clinical samples into the tissue bank program to bolster our understanding of the MBD TIME. Through collaboration with the Monument lab, we are further interested in exploring tumour immune reprogramming in MBD and sarcoma in the context of B-lymphocytes and the induction of durable anti-tumour immune responses via tertiary lymphoid structures. 

Our clinical MBD program has established a large multi-centered Southern Alberta MBD surgical database over the past 8 years that is now incorporated into the international Bone Metastasis Registry. This database is unique in its granularity and size, with high-resolution data from over 590 patients from Alberta. One of our current initiatives is to enact prospective data collection including patient reported outcome measures (PROs), and to continue to pursue patient-engaged research. We have several ongoing projects evaluating surgical outcomes and care delivery in MBD patients with aim to ultimately improve clinical pathways and surgical outcomes. 


More Information

Annalise Abbott
Orthopaedic Surgery Resident Researcher

Ben Wajda
Orthopaedic Surgery Resident Researcher

Leah Ferrie
Medical Student Researcher

Brett Lavender
Medical Student Researcher