Jong Rho
Positions
Full Professor
Cumming School of Medicine, Department of Clinical Neurosciences
Associate Member
Hotchkiss Brain Institute
Full Professor
Cumming School of Medicine, Department of Pediatrics
Contact information
Phone number
Office: (403) 955-2635
Background
Educational Background
B.A. Biochemistry, Yale University, 1977
Doctor of Medicine Medicine, , 1987
Research
Areas of Research
The major goal of our laboratory is to elucidate the molecular and cellular mechanisms underlying the clinical anticonvulsant effects of the ketogenic diet (KD), an effective non-pharmacological treatment for medically refractory epilepsy. We are also attempting to validate the neuroprotective (and potentially) disease-modifying effects of the KD. Recent published studies have focused on the antioxidant properties of ketone bodies – which are produced during KD treatment – and fatty acids (particularly, polyunsaturated fatty acids). The laboratory utilizes cellular in vitro electrophysiological techniques (i.e., single-channel and whole-cell patch-clamp, and IR-DIC slice recordings), combined with molecular genetic approaches, behavioral assessments (e.g., continuous video-EEG monitoring, high-density multi-electrode recordings of brain slices), and cellular fluorescence imaging. The principal animal model of epilepsy studied in our laboratory is the epileptic Kcna1-null mouse, which develops spontaneous recurrent seizures early in post-natal development.
Awards
- award, 2016
- award, 2014
- commendation, 2014
- award, 2013
- Designation as a Best Doctor, Best Doctors, Inc. (www.bestdoctors.com), Aiken, South Carolina. 2009
- Honours, 1999
- Honours, 1998
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