Ian Lewis
Positions
Associate Professor
Director, Alberta Centre for Advanced Diagnostics
UCalgary Research Excellence Chair
Full Member
The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases
Contact information
Background
Educational Background
Bachelor of Science (Summa Cum Laude), Biology, Fort Lewis College, 2003
Doctor of Philosophy, Biochemistry, University Wisconsin - Madison, 2010
Postdoctoral Fellow, Lewis-Sigler Institute , Princeton University, 2014
Visiting Fellow, Harvard T.H. Chan School of Public Health, Harvard University, 2024
Research
Areas of Research
Infectious diseases account for the majority of deaths in developing countries and are among the ten leading causes of mortality in Alberta. The emergence of diverse drug resistant pathogens has made finding new antimicrobial therapies both a Canadian and global health priority. My laboratory investigates the connection between metabolic adaptation and virulence of human pathogens. The ultimate goal of this research is to develop new diagnostic methods to identify high risk patients and novel antimicrobial therapies to control infections. One of the key challenges my laboratory faces is unraveling the complex host-pathogen metabolic dynamics that occur during infections. To address this challenge, we use state-of-the-art mass spectrometry (MS) and nuclear magnetic resonance (NMR) technology to comprehensively quantify the flow of molecules between pathogens and their hosts. This metabolomics approach is a powerful strategy for connecting metabolic phenomena with specific genes and is essential for understanding the metabolic determinants of virulence.
Courses
| Course number | Course title | Semester |
|---|---|---|
| BCEM 443 | Metabolism | Fall 2022 |
Awards
- Innovation Award – Early Career Researcher, University of Calgary. 2021
- Peak Scholar, University of Calgary. 2019
- Compelling Calgarian of 2016, Calgary Herald. 2016
- Alberta Innovates Chair in Translational Health, Alberta Innovates Chair in Translational Health. 2015
- Graduate Mentoring Award, 2007
Publications
In the News
- UofC study helps physicians battle dangerous bacteria.. CBC News. (2018)
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