Graham Thompson

Dr. Graham Thompson



Associate Professor

Cumming School of Medicine, Department of Pediatrics

Associate Professor

Cumming School of Medicine, Department of Emergency Medicine

Care Transformation for Children Program Director

Alberta Children's Hospital Research Institute

Medical Lead - Pediatric Emergency Medicine Research Associate Program

Alberta Childrens Hospital

Contact information


Educational Background

FRCPC Pediatric Emergency Medicine, University of Calgary, 2005

FRCPC Pediatrics, Western University, 2004

Doctor of Medicine Medicine, Western University, 2000

B.Sc. (Hons) Biological Sciences, Messiah University, 1996


Dr. Thompson loves his work caring for acutely ill and injured children at the Alberta Children's Hospital Emergency Department. He is a clinical researcher focusing on improving diagnostics and management of children with appendicitis and sepsis.

His real passion is being out in the mountains where he can often be found running around with his family.


Areas of Research

Pediatric Emergency Medicine, Appendicitis, Sepsis, Inflammation, Precision Medicine

Participation in university strategic initiatives


Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (PRoMPT BOLUS)

Sepsis and septic shock are life-threatening emergencies in children. Despite widespread implementation of resuscitation protocols, in-hospital mortality from sepsis in children in Canada remains at 5%. 

Two types of crystalloid fluids are used for rapid resuscitation in sepsis: Normal Saline (NS) or Balanced Fluid (BF). The goal of this international trial is to determine if resuscitation of children presenting to the Emergency Department in septic shock with BF has improved clinical outcomes compared to those resuscitated with NS.

PRecision Medicine for Improving diagnosis and management of appendicitis in the Emergency Department (PRIMED)

Accurate, timely diagnosis is important to decrease the risk of serious complications in appendicitis in children. The goal of the PRIMED study is to identify unique “bioprofiles”, like fingerprints, in the blood and urine of children with suspected appendicitis. These profiles can be integrated into point-of-care clinical tests to rapidly identify children at risk.