Dr. Gesche Riabowol née Tallen
Positions
Associate Professor
Cumming School of Medicine, Department of Pediatrics
Child Health & Wellness Researcher
Alberta Children's Hospital Research Institute
Pediatric Oncologist
~ Other ~
Contact information
Web presence
Research
Areas of Research
Title of Study: Implementation of a Pharmacogenomic Adverse Drug Reaction (ADR) Prevention Program at Alberta Children’s Hospital
The purpose of this study is to implement a genetic testing program at Alberta Children’s Hospital for children receiving cisplatin, anthracycline, and/or thiopurine chemotherapy, and to determine the utility of this program in preventing adverse reactions to these drugs.
Specific goals of the study are:
(1) Provide doctors who treat children with cancer with the clinical practice guidelines developed for genetic testing to determine a child’s risk of cisplatin-induced hearing loss, anthracycline-induced heart problems, and thiopurine-induced bone marrow suppression (decrease in blood cells).
(2) Provide results of this genetic testing to the doctors caring for patients in this study, as well as to the patients/families.
(3) Determine the usefulness of the genetic testing to doctors and patients and families
Rationale: The identification and development of predictive genetic markers will ultimately help to reduce anthracycline-induced cardiotoxicity, thiopurine-induced immunosuppression and cisplatin-induced ototoxicity, thereby improving the safety of cancer therapy and reducing late effects.
Participation in university strategic initiatives
Courses
Course number | Course title | Semester |
---|---|---|
UME | RIME | current |
Awards
- Dr. Mildred Scheel-Research Scholarship, German Cancer Foundation. 1998
- Kind-Philipp-Research Scholarship, Kind Philipp Leukemia Foundation. 2000
- Magna cum Laude, PhD-Program, University of Hamburg, Germany. 2021
- With great Honours, MD-Program, University of Hamburg, Germany. 1994
- 2 x Bronze-, 1 x Silver-Award & Letter of Excellence for teaching contributions in Medical Skills, University of Calgary, Cumming School of Medicine, UME. 2016
- Honour Roll-Membership in Acknowledgement of Excellent Contribution to Medical Education, University of Calgary, Cumming School of Medicine, UME. 2017
- Platinum Award & Letter of Excellence for Teaching, University of Calgary, Cumming School of Medicine, UME. 2017
- Gold Star Award for Outstanding Teaching during Ethics, University of Calgary, Cumming School of Medicine, Class 2019. 2018
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