Gesche Riabowol

Dr. Gesche Riabowol née Tallen

MD, PhD

Positions

Associate Professor

Cumming School of Medicine, Department of Pediatrics

Child Health & Wellness Researcher

Alberta Children's Hospital Research Institute

Pediatric Oncologist

~ Other ~

Contact information

Research

Areas of Research

Cancer, Genomics, Pharmacotherapy, Knowledge Translation, Quality Improvement, Child Welfare

 

Title of Study: Implementation of a Pharmacogenomic Adverse Drug Reaction (ADR) Prevention Program at Alberta Children’s Hospital

The purpose of this study is to implement a genetic testing program at Alberta Children’s Hospital for children receiving cisplatin, anthracycline, and/or thiopurine chemotherapy, and to determine the utility of this program in preventing adverse reactions to these drugs.

Specific goals of the study are:
(1) Provide doctors who treat children with cancer with the clinical practice guidelines developed for genetic testing to determine a child’s risk of cisplatin-induced hearing loss, anthracycline-induced heart problems, and thiopurine-induced bone marrow suppression (decrease in blood cells).
(2) Provide results of this genetic testing to the doctors caring for patients in this study, as well as to the patients/families.
(3) Determine the usefulness of the genetic testing to doctors and patients and families

Rationale: The identification and development of predictive genetic markers will ultimately help to reduce anthracycline-induced cardiotoxicity, thiopurine-induced immunosuppression and cisplatin-induced ototoxicity, thereby improving the safety of cancer therapy and reducing late effects.

Participation in university strategic initiatives

Courses

Course number Course title Semester
UME RIME current

Awards

  • Dr. Mildred Scheel-Research Scholarship, German Cancer Foundation. 1998
  • Kind-Philipp-Research Scholarship, Kind Philipp Leukemia Foundation. 2000
  • Magna cum Laude, PhD-Program, University of Hamburg, Germany. 2021
  • With great Honours, MD-Program, University of Hamburg, Germany. 1994
  • 2 x Bronze-, 1 x Silver-Award & Letter of Excellence for teaching contributions in Medical Skills, University of Calgary, Cumming School of Medicine, UME. 2016
  • Honour Roll-Membership in Acknowledgement of Excellent Contribution to Medical Education, University of Calgary, Cumming School of Medicine, UME. 2017
  • Platinum Award & Letter of Excellence for Teaching, University of Calgary, Cumming School of Medicine, UME. 2017
  • Gold Star Award for Outstanding Teaching during Ethics, University of Calgary, Cumming School of Medicine, Class 2019. 2018