Dave Schriemer

Dr. David Schriemer, MSc, PhD

Positions

Professor

Cumming School of Medicine, Department of Biochemistry and Molecular Biology

Adjunct Professor

Faculty of Science, Department of Chemistry

Member

Arnie Charbonneau Cancer Institute

Child Health & Wellness Researcher

Alberta Children's Hospital Research Institute, Owerko Centre

Member

Robson DNA Science Centre

Contact information

Phone number

Office: 403.210.3811
Lab: 403.220.4202

Location

Office: HSCB031

Admin Assistant

Jumi Lee

Email: jumi.lee@ucalgary.ca

Office: 403.210.3907

Background

Educational Background

B.S. Chemistry, University of Winnipeg, 1991

Doctor of Philosophy Chemistry, University of Alberta, 1997

M.S. Chemistry, University of Manitoba, 1993

Biography

Dr.Schriemer is an academic and entrepreneur. He graduated with degrees in organic chemistry and bioanalytical chemistry and received further training in biochemistry during postdoctoral work. He was the founder of INH Technologies Inc., a biotech startup in Calgary, and served as Research Director in MDS Proteomics Inc. before joining the Department of Biochemistry & Molecular Biology at the University of Calgary in 2001. Dr. Schriemer’s laboratory maintains a basic research program in integrative structural biology of complex systems, incorporating proteomics technologies, reagent development and computational methods. His goal is to move beyond a “building block” understanding of protein structure and function, and into a world where protein function is understood at high resolution, in the context of protein complexes, networks and whole proteomes. Dr. Schriemer has been a Canada Research Chair in Chemical Biology and a Senior Scholar of the Alberta Heritage Foundation for Medical Research. He served as the director of the SAMS Centre for Proteomics until 2017 and is currently Chief Science Officer and Director of Nepetx LLC. His latest translational project involves establishing a scientific software development company.

Research

Areas of Research

Area of Focus
  • Integrative structural biology
  • Clinical proteomics
Summary of Research

i. Integrative structural biology

Our laboratory maintains a fundamental research program in structural biology. We are interested in understanding how the governing principles behind molecular interactions serve to organize protein function at a scale beyond that of the individual protein. Using the tools of proteomics, structural biology and computational modeling (AI), we study structure-function relationships in large multicomponent protein systems, with a view to understanding how function can be regulated at this “mesoscale”. We are actively involved in developing the mass spec technology as a key provider of modeling data and work to move structure determination closer to cellular-level activity. 

ii. Clinical proteomics

We are developing new strategies for achieving accurate and comprehensive proteome coverage of clinically-relevant samples, in order to discover and characterize molecular markers of disease. We implement the latest methods in quantitative and discovery proteomics and develop new  concepts to improve our ability to detect markers of neurological disorders and new immunotherapy targets for cancer.

Courses

Course number Course title Semester
MDGE 622 LEC 01 01 Princ & Appl of Proteomics 2020
MDGE 726 LAB 01 B01 Applied Structural Biology 2021

Awards

  • Shultz Award for General Excellence, Biochemistry & Molecular Biology. 2017
  • Peak Scholar, University of Calgary. 2015
  • Associate Prof. Departmental Achievement Award, Biochemistry & Molecular Biology. 2014
  • Associate Prof. Departmental Achievement Award, Biochemistry & Molecular Biology. 2013
  • Cochrane Distinguished Achievement Award for Excellence in Research, Cumming School of Medicine. 2011
  • Associate Prof. Departmental Achievement Award, Biochemistry & Molecular Biology. 2011
  • Cochrane Distinguished Achievement Award for Excellence in Research, Cumming School of Medicine. 2009
  • Associate Professor Achievement Award , Biochemistry & Molecular Biology. 2009
  • Heritage Senior Scholar Award, Alberta Heritage Foundation for Medical Research . 2009
  • Canada Research Chair in Chemical Biology, Govt. of Canada. 2009
  • Canada Research Chair, Govt. of Canada. 2004
  • Heritage Scholar Award, Alberta Heritage Foundation for Medical Research . 2004
  • Leica Rising Star Award , Biochemistry & Molecular Biology. 2003
  • Cochrane Distinguished Achievement Award for Excellence in Research, Cumming School of Medicine. 2003

Publications

In the News