Dr. David Lindenbach
Positions
Adjunct Assistant Professor
Cumming School of Medicine, Department of Psychiatry
Child Health & Wellness Researcher
Alberta Children's Hospital Research Institute
Affiliations
Associate Member
Hotchkiss Brain Institute
Associate Member
Mathison Centre for Mental Health Research and Education
Contact information
Phone number
Cell: 403.830.7371
Location
Office: Hull Services, 2266 Woodpark Ave SW, CalgaryBuilding M
I'm looking for...
Research partners
I am building a new program of research centred around the prevention and treatment of developmental trauma, and am looking to build collaborations.
Funding
We are also looking for funding to grow our research around developmental trauma.
Background
Educational Background
PhD Behavioral Neuroscience, State University of New York at Binghamton,
MS Psychology, State University of New York at Binghamton,
BA Sociology, Willamette University,
Biography
Throughout my career, I have had a passion for developing and testing therapeutics for brain disorders.
In 2009, I began a PhD examining treatments for Parkinson’s disease using rat models. Next, I did a post-doctoral fellowship examining the neural circuits involved in motivation with an eye towards using brain stimulation as a treatment for anhedonia in mental illness. In 2018, I came to the University of Calgary because I wanted to perform clinical research that had a direct impact on service delivery in community settings.
In 2018, I re-focused my career towards preventing child maltreatment and developing therapies for youth exposed to trauma. As a Research Associate in Psychiatry, I performed research with schools, non-profits and AHS clinics to identify how frontline providers assess risk for maltreatment. In the same settings, I also used implementation science methods to identify how we can use novel transdiagnostic cognitive behavioural therapies to support families impacted by trauma and mental illness.
In 2023, I joined Hull Services to lead the development of a new program of research into developmental trauma as part of an official partnership with the University of Calgary's Mathison Centre for Mental Health Research & Education and the Faculty of Social Work. Our research involves child maltreatment prevention and early intervention; therapeutic recreation for youth impacted by trauma; improving the success of transitions in care; and promoting wellness and professional development among frontline care providers. I strongly believe in involving clients and clinicians in research design and analysis because this maximizes the relevancy and sustainability of clinical research. I am passionately committed to EDI, especially working with Indigenous Elders and cultural advisors to incorporate Indigenous ways of being, knowing and doing into research. I also leverage my diverse research background to pursue a transdisciplinary line of research that incorporates biological, psychological and sociological perspectives because I believe a holistic approach is needed to heal the impact of developmental and intergenerational trauma on youth and families.
Research
Participation in university strategic initiatives
Projects
Nominated Principal Applicant. Alberta Children’s Hospital Research Institute: One Child Every Child Seedling Award. $50,000. 2024 - 2026.
Principal Investigator. Burns Memorial Fund for Children: Community Grant. $15,000. 2024 - 2025.
Project Holder. Parks Foundation Calgary: Amateur Sport Grant. $50,000. 2024 - 2025.
Project Holder. University of Calgary: Transdisciplinary Scholarship Connector Grant. $17,000. 2024.
Co-applicant. Canadian Consortium on Child & Youth Trauma: Seed Grant. $25,000. 2023 - 2024.
Co-applicant. Canadian Institutes of Health Research: Catalyst Grant. $199,960. 2023 - 2024.
Co-applicant. Canadian Institutes of Health Research Team Grant: Transitions in Care. $960,000. 2022 - 2026.
Co-investigator. City of Calgary: Mental Health and Addiction Investment Framework. $471,525. 2022 - 2023.
Co-investigator. Social Science and Humanities Research Council: Partnership Grant. $2,500,000. 2020 - 2027.
Co-investigator. Government of Alberta: Mental Health and Addiction COVID-19 Community Funding Grant. $48,000. 2020 - 2021.
Co-investigator. University of Calgary: COVID-19 Giving Day Funding Opportunity. $10,000. 2020 - 2021.
Co-investigator. Binghamton University: Transdisciplinary Areas of Excellence Seed Grant. $15,000 USD. 2015.
Co-investigator. Michael J. Fox Foundation: Rapid Response Innovation Award. $75,000 USD. 2015.
Awards
- Evolve to Innovate Trainee Award, Innovate Calgary. 2022
Publications
- Feasibility and acceptability of implementing a transdiagnostic cognitive behavioral therapy for children impacted by trauma within a residential treatment facility. Lindenbach, D., Anderson, A., Wang, E., Heintz, M., Rowbotham, M., Ehrenreich-May, J., Arnold, P.D. & Dimitropoulos, G . Child & Youth Services. 1-26. (2024)
- Using a rapid learning health System for stratified care in emerging adult mental health services: Protocol for the implementation of patient-reported outcome measures. Dimitropoulos, G., Lindenbach, D., Potestio, M., Mogan, T., Richardson, A., Anderson, A., Heintz, M., Moskovic, K., Gondziola, J., Bradley, J., La Monica, H., Iorfino, F., Hickie, I.B., Patten, S.B. & Arnold, P.D. JMIR Research Protocols. 13. (2024)
- A qualitative study on the implementation of a transdiagnostic cognitive behavioral therapy for children in a child welfare residential treatment program. Dimitropoulos, G., Lindenbach, D., Anderson, A., Rowbotham, M., Wang, E., Heintz, M., Ehrenreich-May, J. & Arnold, P.D. Child Abuse & Neglect. 146, 106487. (2023)
- Feasibility and acceptability of a brief, online transdiagnostic psychotherapy for young adults. Dimitropoulos, G., Lindenbach, D., Rowbotham, M., Devoe, D.J., Richardson, A., Mogan, T., Patten, S.B., Ehrenreich-May, J. & Arnold, P.D. Journal of the Canadian Academy of Child & Adolescent Psychiatry. 32(2): 111-125. (2023)
- A trauma-informed approach to the Unified Protocol for Children with exposure to child maltreatment. Gruen, R., Lindenbach, D., Ehrenreich-May, J., Arnold, P. & Dimitropoulos, G. In Shenk, C. (Ed.). Innovative Methods in Child Maltreatment Research and Practice. 199-225. (2023)
- Recommendations for a comprehensive youth mental health strategy for Alberta. Arnold, P.D., Dimitropoulos, G., Lindenbach, D., Zwicker, J., & Greer, K. Alberta 2023: Health System Challenges and Opportunities. (2023)
- Optogenetic modulation of glutamatergic afferents from the ventral subiculum to the nucleus accumbens: Effects on dopamine function, response vigor and locomotor activity. Lindenbach, D., Vacca, G., Ahn, S., Seamans, J.K. & Phillips, A.G. Behavioural Brain Research . 434, 114028. (2022)
- Experiences of Canadian mental health providers in identifying and responding to online and in-person sexual abuse and exploitation of their child and adolescent clients. Dimitropoulos, G.*, Lindenbach, D.*, Devoe, D.J., Gunn, E., Cullen, O., Bhattarai, A., Kuntz, J., Binford, W. & Arnold, P.D. Child Abuse & Neglect. 124, 105448. *co-first authors. (2022)
- Confidence, training and challenges for Canadian child advocacy center staff when working with cases of online and in-person child sexual exploitation. Lindenbach, D., Dimitropoulos, G., Bhattarai, A., Cullen, O., Perry, R, Arnold, P.D. & Patten, S.B. Journal of Child Sexual Abuse. 31, 297-315. (2022)
- Push 2 Heal: Pilot Project. Final evaluative report. Co-author. (2022)
- Capacity, confidence and training of Canadian educators and school staff to recognize and respond to sexual abuse and internet exploitation of their students. Lindenbach, D., Cullen, O., Bhattarai, A., Perry, R., Diaz, R.L., Patten, S.B. & Dimitropoulos, G. Child Abuse & Neglect. 112, 104898. (2021)
- Activation of the ventral subiculum reinvigorates behavior after failure to achieve a goal: implications for the dopaminergic modulation of motivational processes. Lindenbach, D., Seamans, J.K. & Phillips, A.G. Behavioural Brain Research. 356, 266-270. (2019)
- Prior exposure to salient win-paired cues in a rat gambling task increases the sensitivity to cocaine self-administration and suppresses dopamine efflux in nucleus accumbens: support for the reward deficiency hypothesis of addiction. Ferland, J-M.N., Hynes, T.J., Hounjet, C.D., Lindenbach, D., Vonder Haar, C., Adams, W.K., Phillips, A.G. & Winstanley, C.A. Journal of Neuroscience. 39, 1842-1854. (2019)
- D-512, a novel dopamine D2 / D3 receptor agonist, demonstrates superior anti-parkinsonian efficacy over ropinirole in Parkinsonian rats. Lindenbach, D., Das, B., Conti, M.M., Meadows, S.M., Dutta, A.K. & Bishop, C. British Journal of Pharmacology. 174, 3058-3071. (2017)
- The role of primary motor cortex (M1) glutamate and GABA signaling in L-DOPA-induced dyskinesia in Parkinsonian rats. Lindenbach, D., Conti, M.M., Ostock, C.Y., George, J.A., Goldenberg, A.A., Melikhov-Sosin, M., Nuss, E.N. & Bishop, C. Journal of Neuroscience. 36, 9873-9887. (2016)
- Monoamine transporter contributions to L-DOPA effects in hemi-parkinsonian rats. Conti, M.M., Meadows, S., Melikhov-Sosin, M., Lindenbach, D., Hallmark, J., Werner, D.F. & Bishop, C. Neuropharmacology. 110:125-134. (2016)
- Effect of tricyclic antidepressants on L-DOPA-induced dyskinesia and motor improvement in hemi-Parkinsonian rats. Conti, M.M., Goldenberg, A.A., Kuberka, A., Mohamed, M., Eisa, S., Lindenbach, D., & Bishop, C. Pharmacology, Biochemistry and Behavior. 142, 64-71. (2016)
- Alterations in primary motor cortex neurotransmission and gene expression in a rat model of Parkinson’s disease and drug-induced dyskinesia. Lindenbach, D., Conti, M.M., Ostock, C.Y., Dupre, K.B. & Bishop, C. Neuroscience. 310, 12-26. (2015)
- Effects of the beta-adrenergic receptor antagonist Propranolol on dyskinesia and L-DOPA-induced striatal DA efflux in the hemi-parkinsonian rat. Bhide, N., Lindenbach, D., Barnum, C.J., George, J.A., Surrena, M.A. & Bishop, C. Journal of Neurochemistry. 134, 222-232. (2015)
- Side-effect profile of serotonergic treatments for Parkinson’s disease and L-DOPA-induced dyskinesia in rats. Lindenbach, D., Palumbo, N., Ostock, C.Y., Vilceus, N., Conti, M.M. & Bishop, C. British Journal of Pharmacology. 172, 119-130. (2015)
- Effects of noradrenergic denervation by anti-DBH-saporin on behavioral responsivity to L-DOPA in the hemi-parkinsonian rat. Ostock, C.Y., Lindenbach, D., Goldenberg, A.A., Kampton, E. & Bishop, C. Behavioral Brain Research. 270, 75-85. (2014)
- Effects of prolonged selective serotonin reuptake inhibition on the development and expression of L-DOPA-induced dyskinesia in hemi-parkinsonian rats. Conti, M.C., Ostock, C.Y., Lindenbach, D., Goldenberg, A.A., Kampton, E., Dell’isola, R., Katzman, A. & Bishop, C. Neuropharmacology. 77, 1-8. (2014)
- Critical involvement of the motor cortex in the pathophysiology and treatment of Parkinson’s disease. Lindenbach, D. & Bishop, C. Neuroscience and Biobehavioral Reviews. 37, 2737-2750. (2013)
- Effects of 5-HT1A receptor stimulation on striatal and cortical M1 pERK induction by L-DOPA and a D1 receptor agonist in a rat model of Parkinson’s disease. Lindenbach, D., Dupre, K.B., Eskow Jaunarajs, K.L., Ostock, C.Y., Goldenberg, A.A. & Bishop, C. Brain Research. 1537, 327-339. (2013)
- The effects of BMY-14802 against L-DOPA and DA agonist-induced dyskinesia in the hemiparkinsonian rat. Bhide, N., Lindenbach, D., Surrena, M.A., Goldenberg, A.A., Bishop, C., Berger, S.P. & Paquette, M.A.. Psychopharmacology. 227, 533-544. (2013)
- Effects of noradrenergic deneveration on L-DOPA-induced dyskinesia and it’s treatment by α- and β-adrenergic receptor antagonists in hemiparkinsonian rats. Barnum, C.J., Bhide, N., Lindenbach, D., Surrena, M.A., Goldenberg, A.A., Tignor, S., Klioueva, A., Walters, H. & Bishop, C. Pharmacology Biochemistry and Behavior. 100, 607-615. (2012)
- Behavioral and cellular modulation of L-DOPA-induced dyskinesia by β-adrenoceptor blockade in the 6-hydroxydopamine-lesioned rat. Lindenbach, D., Ostock, C.Y., Eskow Jaunarajs, K.L., Dupre, K.B., Barnum, C.J., Bhide, N. & Bishop, C. Journal of Pharmacology and Experimental Therapeutics. 337, 355-365. (2011)
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