Christophe Altier

Dr. Christophe Altier

Positions

Professor

Cumming School of Medicine, Department of Physiology and Pharmacology

Full Member

The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases

Full Member and Chair

Inflammation Research Network

Associate Member

Hotchkiss Brain Institute

Child Health & Wellness Researcher

Alberta Children's Hospital Research Institute

Contact information

Web presence

Phone number

Office: +1.403.220.7549
Lab: +1.403.220.3696

Location

Office: HSC 1665
Lab: HSC 1604

Background

Educational Background

Ph.D. Neurobiology, University of Montpellier, 2002

M.Sc. Neurobiology, University of Montpellier, 1999

M.Sc. Physiology, University of Montpellier, 1997

Research

Areas of Research

Our research focus is on the neurobiology of pain, with a particular interest in understanding the plasticity of specialized sensory neurons (nociceptors) in chronic diseases (i.e arthritis, inflammatory bowel disease (IBD) or cancer).

By combining diverse techniques, including molecular biology, RNAscope in human sample biopsies, genetically modified mice, chemogenetics, and behavioral analysis in clinically relevant mouse models of pathological pain, we investigate the signaling pathways that mediate pain or promote its resolution. The goal of our research is to make discoveries on novel pain biomarkers and signal transducers that contribute to pain chronification and could be targeted for treatments. Our lab also uses interdisciplinary approaches in germ free and gnotobiotic mouse models to uncover the role of bacteria and their metabolites in pain sensitivity.

Publications

Valerie Ho
4th year Project Student
valerie.ho1@ucalgary.ca

Aye Ozmaeian
MSc Student
aye.ozmaeian1@ucalgary.ca

Nasser Abdullah
PhD Student
nasser.abdullah@ucalgary.ca

Mélissa Cuménal, PhD
Postdoctoral Fellow
melissa.cumenal@ucalgary.ca

Manon Defaye, PhD
Postdoctoral Fellow
manon.defaye1@ucalgary.ca

Amyaouch Bradaia, PhD
Research Associate
amyaouch.bradaia@ucalgary.ca

Barbara Chyz
HSC 1663
Email: chyz@ucalgary.ca
Phone:+1.403.220.4555