Dr. Brent Edwards, PhD
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Faculty of Kinesiology
Schulich School of Engineering, Department of Biomedical Engineering
McCaig Institute for Bone and Joint Health
Leanne Yohemas - Director, Communications and Marketing, Faculty of Kinesiology.
PhD Biomechanics, Iowa State University, 2009
MSc Biomechanics, California State University, Sacramento, 2005
BSc Kinesiology, Exercise Science, California State University, Sacramento, 2003
|Course number||Course title||Semester|
|KNES 393||Research Seminar l||Fall 2021|
|KNES 395||Research Seminar II||Fall 2021|
|KNES 664||Bone and Joint Biomechanics||Fall 2021|
Mechanical fatigue of load bearing biological tissue is an inevitable consequence of physical activity. Over time, habitual loading of the musculoskeletal system causes microdamage accumulation that reduces the overall quality of the tissue and leads to a reduction in stiffness and an increase in mechanical strain with continued loading. Without adequate tissue repair and adaptation, the evolution and accumulation of microdamage may eventually lead to musculoskeletal injury. Mechanical fatigue is believed to play a predominant role in the pathophysiology of musculoskeletal injuries such as bone stress fracture as well as Achilles and patellar tendinopathy.
Our research combines biomechanical experimentation with advanced medical imaging and computational modeling to investigate tissue damage and fatigue in response to mechanical loading. Our unique approach allows us to estimate in vivo tissue mechanics in a non-invasive and subject-specific manner. The work in our group spans multiple dimensional scales, from basic experiments at the tissue-level that enhance our understanding of the mechanical fatigue process, to applied experiments at the whole-body level for the development of treatments and interventions to improve tissue quality and decrease injury risk.