Braedon McDonald
Positions
Associate Professor
Cumming School of Medicine, Department of Critical Care Medicine
Intensive Care Specialist
Foothills Medical Centre, Alberta Health Services
Full Member
The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases
Full Member
Inflammation Research Network
Contact information
Phone number
Office: 403.220.6885
Lab: 403.220.4423
Location
Lab: HSC 1718
Background
Credentials
FRCPC -Critical Care Medicine, University of Calgary, 2018
FRCPC -Internal Medicine, University of British Columbia, 2016
Educational Background
Postdoctoral Fellowship - Microbiome and Immunity -, International Microbiome Centre, University of Calgary, 2020
PhD - Immunology, University of Calgary, 2013
MD University of Calgary, 2013
BSc - Microbiology and Immunology, McGill University, 2007
Biography
Dr. Braedon McDonald is an Assistant Professor in the Department of Critical Care Medicine and Department of Medicine in the Cumming School of Medicine. Originally from Crossfield, AB, Dr. McDonald trained in microbiology and immunology at McGill University in Montreal, followed by MD as well as PhD training in immunology at the University of Calgary. He completed Internal Medicine residency at the University of British Columbia, followed by a fellowship in adult Critical Care Medicine at the Cumming School of Medicine. Dr. McDonald completed a CIHR- and AIHS-funded postdoctoral fellowship in microbiome research at the University of Calgary’s International Microbiome Centre. Dr. McDonald is a clinician-scientist in the Snyder Institute for Chronic Diseases and International Microbiome Centre, where he leads a translational and basic science research program on microbiome-immune interactions in infection and critical illness. Dr. McDonald’s clinical practice focuses on multi-systems intensive care, and he is an attending intensivist in the ICU at FMC, RGH, and SHC.
Research
Participation in university strategic initiatives
Projects
1. Microbiology and immunology of infections and sepsis in the ICU.
- Gut microbiota dysbiosis in the pathogenesis of nosocomial infections and organ dysfunction in the ICU.
- Multi-dimensional profiling of microbiota-immune interactions in ICU patients.
- Host-microbe interactions and immune dysfunction in critical illness.
2. Microbiota-immune interactions in the regulation of host defense against infections and sepsis.
- Intravital imaging of host-microbe interactions in vivo.
- Germ-free and gnotobiotic models of ICU dysbiosis.
- Cellular and molecular mechanisms of microbiota-immune interactions during sepsis and critical illness.
3. Translational research into precision therapeutics for the prevention and treatment of infections and sepsis in the ICU.
- Development of precision microbiota-editing strategies to modulate microbiota-immune mutualism.
- Immunotherapy for the treatment of infections and sepsis.
Publications
More Information
Katrina Yu
Lab Manager
ianling.yu@ucalgary.ca
Matthew Stephens, PhD
Research Associate
matthew.stephens@ucalgary.ca
Niki Cho
Postdoctoral Fellow
nacho@ucalgary.ca
Colin MacKenzie
Postdoctoral Fellow
colin.mackenzie1@ucalgary.ca
Jared Schlechte
PhD candidate
jared.schlechte@ucalgary.ca
Ayesha Wijesinghe
PhD student
ayesha.wijesinghe@ucalgary.ca
Kathryn Strayer
MSc student
kathryn.strayer1@ucalgary.ca
Anthony Machado
CMMB Honours Project student
anthony.machado@ucalgary.ca
Angie Lamb
Email: alamb@ucalgary.ca
Phone: 403.210.8635
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