Dr. A.P. Jason de Koning
Positions
Associate Professor
Cumming School of Medicine, Department of Biochemistry and Molecular Biology
Graduate Program Director
Cumming School of Medicine, Department of Biochemistry and Molecular Biology
Child Health & Wellness Researcher
Alberta Children's Hospital Research Institute
Associate Member
Arnie Charbonneau Cancer Institute
Contact information
Background
Educational Background
B.Sc. Computer Science & Biology, Trent University, 1999
PhD Molecular Biology (Comparative Genomics), SUNY (Albany), 2007
Postdoctoral Fellow Computational Genomics and Bayesian Statistics, University of Colorado Denver, School of Medicine, 2012
Research
Areas of Research
- Comparative, statistical, and personal genomics
- Enabling high through-put inference from large genomic datasets using novel computational, statistical, and bioinformatic approaches
- Predicting the functional impact and clinical significance of sequence variation in individual human genomes
- Molecular evolution
My research interests are chiefly in the areas of computational and statistical genomics. My lab is particularly interested in developing high-throughput computational approaches that will help maximize the utility of large-scale comparative, population, and cancer genome datasets using large-scale inference and modelling paradigms from population genetics. In cancer genomics, we are primarily interested in ways to identify driver genes in tumour-normal samples and in the population genetics and functional evolution of somatic clones.
Participation in university strategic initiatives
Courses
| Course number | Course title | Semester |
|---|---|---|
| MDGE 75503 LEC 01 01 | Directed Studies | 2020 |
| MDSC 308 LEC 01 01 | Interdisc Research Approaches | 2021 |
| MDSC 679 LAB 01 B01 | Fundamentals of Bioinformatics | 2020 |
| MDSC 679 LEC 01 01 | Fundamentals of Bioinformatics | 2021 |
| MDSC 308 LEC 01 01 | Interdisc Research Approaches | 2020 |
Publications
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