Alvin Joselin
Positions
Adjunct Research Assistant Professor
Cumming School of Medicine, Department of Clinical Neurosciences
Research Manager
Cumming School of Medicine, Department of Clinical Neurosciences
Associate Member
Hotchkiss Brain Institute
Contact information
Background
Educational Background
PhD Molecular Biology, Heinrich-Heine-Universität Düsseldorf,
MSc Microbiology, Bharathidasan University,
Biography
Dr. Joselin is a Research Assistant Professor in the department of Clinical Neurosciences, Cumming School of Medicine at the University of Calgary. He leads a research team consisting of laboratory staff, postdoctoral fellows, and students. Prior to joining the University of Calgary, Dr. Joselin was engaged in research at the department of Cellular and Molecular Medicine, University of Ottawa.
Dr. Joselin has over a decade of experience woking in the field of Neurodegeneration and has published in high impact journals such as Journal of Biological Chemistry, Human Molecular Genetics and Proceedings of the National Academy of Sciences. As an early career investigator, Dr. Joselin is research currently centers around understanding the molecular mechanisms involved in the pathogenesis of Parkinson's Disease (PD) using genetic rodent models of PD.
Research
Areas of Research
Dr. Joselin's research interests are in the field of neurodegeneration. He has focused his research efforts on understanding the death pathways that control neurodegeneration, particularly relating to Parkinson's Disease and the mechanisms and function of PD linked genes. In the past several years, Dr. Joselin has been involved in studies that define the pathways important in neuronal death using animal models. His current research focuses on the intersection of mitochondrial dynamics, endoplasmic reticulum (ER) stress and their implications on neurodegeneration via the regulation of cell death pathways and/or the activation of neuro-immunological responses. Towards this goal, Dr. Joselin's research strategy includes;
- Investigating the role of the proteins associated with the diseases and their contribution to the many cellular pathways they are involved in and
- Manipulating these mechanisms to understand their contribution to the overall health of the cell and its interaction with the other major cell types of the brain.
Participation in university strategic initiatives
Publications
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